How Natera designed an agentic AI system for lab ops with Amazon Bedrock AgentCore

At Natera, a leader in cell-free DNA (cfDNA) testing, keeping lab instruments up and running is critical, because equipment downtime disrupts sample processing. Natera’s lab engineering team, led by Ariel Jirau worked with AWS to build SWARM (Systematic Workflow Analytics and Resolutions Manager), an agentic AI system for lab operations. This post walks through how the Natera team built an agentic AI system for lab operations using Amazon Bedrock AgentCore that captures and deploys institutional knowledge at scale. It describes the full architecture, from knowledge base construction to automated system deployment and evaluation, so you can apply the same patterns to your own operational workflows….