Discovery of cells that keep immune responses in check wins medicine Nobel Prize
Text settings Story text Size Small Standard Large Width * Standard Wide Links Standard Orange * Subscribers only Learn more Minimize to nav Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi were awarded the 2025 Nobel Prize in Physiology or Medicine on Monday for their collective work in the discovery of specialized immune cells that roam the body and keep potentially harmful immune responses in check—preventing them from attacking the body directly (autoimmune responses) or causing harm with overzealous responses to invaders. Those specialized cells—regulatory T cells—are now well established as playing a key role in peripheral immune tolerance. That is, a non-central process that allows the immune system to strike a delicate…
